该基因编码的蛋白是ATP结合盒(ABC)转运蛋白的超家族成员。ABC蛋白通过细胞外膜和细胞内膜转运各种分子。ABC基因被分为7个不同的亚家族(abc1、mdr/tap、mrp、ald、oabp、gcn20和white)。这种ABC全转运体是MRP亚家族的一员,涉及多药耐药。已发现编码该基因不同亚型的多种转录变体。
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.

基因名:ABCC10
别名:EST182763,MRP7,SIMRP7
基因ID:89845
Chromosome:
(GRCh37)
6 Start: 43395104 End: 43418168 Strand: 1
信号通路:  
靶向药:
化疗药: 紫杉醇