该基因编码激活的白细胞粘附分子(alcam),也称为CD166(分化簇166),是免疫球蛋白受体的一个亚家族的成员,在细胞外区域有五个免疫球蛋白样结构域(vvc2c2c2)。该蛋白与T细胞分化抗原CD6结合,参与细胞粘附和迁移过程。发现了编码不同亚型的多种选择性剪接转录变体。
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

基因名:ALCAM
别名:CD166,MEMD
基因ID:214
Chromosome:
(GRCh37)
3 Start: 105085753 End: 105295744 Strand: 1
信号通路:  
靶向药:
化疗药: 氟尿嘧啶 
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