双链(ds)RNA特异性内核糖核酸酶III超家族成员参与真核细胞和原核细胞的多种RNA成熟和衰变途径(Fortin等人,2002[PubMed 12191433])。RNase III Drosha是核心核酸酶,执行细胞核中microRNA(microRNA)处理的起始步骤(Lee等人,2003[PubMed 14508493])。
Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003 [PubMed 14508493]).

基因名:DROSHA
别名:ETOHI2,HSA242976,RANSE3L,RN3,RNASE3L,RNASEN
基因ID:29102
Chromosome:
(GRCh37)
5 Start: 31400604 End: 31532303 Strand: -1
信号通路: