该基因编码一种分泌肽激素和表皮生长因子(egf)蛋白家族成员。编码蛋白是表皮生长因子受体(egfr)和结构相关的erb-b2受体酪氨酸激酶4(erbb4)的配体。编码蛋白可能参与多种生物学过程,包括炎症、伤口愈合、卵母细胞成熟和细胞增殖。此外,编码蛋白可能促进各种人体组织癌症的进展。
This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues.

基因名:EREG
别名:EPR,ER,Ep
基因ID:2069
Chromosome:
(GRCh37)
4 Start: 75230860 End: 75254468 Strand: 1
信号通路:  
靶向药: 西妥昔单抗  帕尼单抗 
化疗药: