这个基因编码一个美其辛金属蛋白酶papplayin家族成员。编码的蛋白质分裂胰岛素样生长因子结合蛋白5,被认为是胰岛素样生长因子(IGF)生物利用度的局部调节器。选择性剪接导致多个转录变体。
This gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin-like growth factor-binding protein 5 and is thought to be a local regulator of insulin-like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants.

基因名:PAPPA2
别名:PAPP-A2,PAPP-E,PAPPE,PLAC3
基因ID:60676
Chromosome:
(GRCh37)
1 Start: 176432307 End: 176814735 Strand: 1
信号通路:  
靶向药: 派姆单抗(帕博利珠单抗) 
化疗药:
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