磷脂酰肌醇3-激酶(PI3K)是一种脂质激酶,能磷酸化磷脂酰肌醇和类似化合物,在生长信号传导途径中产生重要的第二信使。PI3K作为调节亚单位和催化亚单位的异二聚体发挥作用。该基因编码的蛋白质是PI3K的调节成分,已发现该基因有两个转录变体,一个蛋白编码,另一个非蛋白编码。
Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene.

基因名:PIK3R2
别名:MPPH,MPPH1,P85B,p85,p85-BETA
基因ID:5296
Chromosome:
(GRCh37)
19 Start: 18263928 End: 18281350 Strand: 1
信号通路: 细胞增殖  免疫相关  炎症相关  血管生成  凋亡抑制  能量代谢 
靶向药: 维莫非尼 
化疗药: