这个基因编码一种蛋白质,作为β-干扰素基因表达的抑制剂。该蛋白与β-干扰素基因启动子的prdi(阳性调节域i元件)特异性结合。这种基因的转录随着病毒的诱导而增加。已经报道了两种编码不同亚型的选择性剪接转录变体。
This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.

基因名:PRDM1
别名:BLIMP1,PRDI-BF1
基因ID:639
Chromosome:
(GRCh37)
6 Start: 106534195 End: 106557814 Strand: 1
信号通路: 基因组不稳定