该基因编码一种与乙型肝炎病毒X蛋白(hbx)相互作用的核蛋白,并通过hbx转录激活剂促进乙型肝炎病毒基因的转录,提示这种相互作用在病毒生命周期中的作用。该蛋白也与snf2h蛋白相互作用,形成rsf染色质重塑复合物,其中snf2h亚单位作为核小体依赖性atpase,该蛋白作为组蛋白伴侣。
This gene encodes a nuclear protein that interacts with hepatitis B virus X protein (HBX) and facilitates transcription of hepatitis B virus genes by the HBX transcription activator, suggesting a role for this interaction in the virus life cycle. This protein also interacts with SNF2H protein to form the RSF chromatin-remodeling complex, where the SNF2H subunit functions as the nucleosome-dependent ATPase, and this protein as the histone chaperone.

基因名:RSF1
别名:HBXAP,RSF-1,XAP8,p325
基因ID:51773
Chromosome:
(GRCh37)
11 Start: 77371041 End: 77532063 Strand: -1
信号通路:  
靶向药:
化疗药: 他莫昔芬 
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