这个基因编码一个核丝氨酸/苏氨酸激酶,最初在拟南芥中被鉴定出来。编码蛋白被认为通过调节组蛋白H3/H4伴侣蛋白的水平来调节细胞周期S期染色质的装配。这种蛋白与辐射引起的DNA损伤的双链断裂修复有关。该基因的假基因存在于染色体10和17上。交替剪接导致多个转录变体。
This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants.

基因名:TLK2
别名:HsHPK,PKU-ALPHA
基因ID:11011
Chromosome:
(GRCh37)
17 Start: 60536019 End: 60692842 Strand: 1
信号通路:  
靶向药: GF109203X Go6983 
化疗药: