这个基因编码锌指转录因子。编码蛋白可能在白细胞介素2的转录抑制中起作用。该基因突变与后多形性角膜营养不良-3和晚发型Fuchs内皮性角膜营养不良有关。另外,还描述了编码不同亚型的剪接转录变体。
This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.

基因名:ZEB1
别名:AREB6,BZP,DELTAEF1,FECD6,NIL2A,PPCD3,TCF8,ZFHEP,ZFHX1A
基因ID:6935
Chromosome:
(GRCh37)
10 Start: 31607424 End: 31818742 Strand: 1
信号通路:  
靶向药:
化疗药: 阿糖胞苷 多柔比星 吉西他滨 盐霉素