该基因属于转录因子的叉头家族，具有独特的叉头结构域。该基因的特异功能尚未确定，但可能在肌源性生长和分化中发挥作用。该基因与pax3的易位与肺泡横纹肌肉瘤有关。
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.