一、题目和背景信息
| 登记号 | CTR20180183（未招募） |
| 首次公示 | 2018-03-23 |
| 药物名称 | Nivolumab |
| 公司 | 百时美施贵宝 |
| 适应症 | 食管癌或胃食管连接部癌 |
| 备注 | 必须患II期或III期食管癌或胃食管连接部癌，并在初始诊断时经组织学证实主要为腺癌或鳞状细胞癌食管或胃食管连接部癌 |
二、申办者信息
| 申办者名称 | 百时美施贵宝 |
| 联系人姓名 | 颜艳 |
| 联系人电话 | 021-23218421 |
| 联系人Email | sarah.yan@bms.com |
| 联系人邮政地址 | 上海市南京西路1717号会德丰国际广场15楼 |
| 联系人邮编 | 200040 |
三、参加医院、医生信息
| 1 上海市胸科医院 | 方文涛 |
| 2 Hospital Municipal De Gastroenterologia Dr.Udaondo | Carballido, Marcela |
| 3 Hospital Aleman | Castillo, Javier |
| 4 Clinica Viedma S.A. | Kowalyszyn, Ruben |
| 5 Fundacion Favaloro | Mendez, Guillermo |
| 6 Hospital Provincial Del Centenario | Ostoich, Sandra |
| 7 Instituto Medico Especialazado Alexander Fleming | O′Connor, Juan Manuel Ramon |
| 8 Centro Para La Atencion Integral Del Paciente Oncologico | Palazzo, Felipe |
| 9 Instituto Oncologico De Cordoba | Richardet, Eduardo |
| 10 Princess Alexandra Hospital | Atkinson, Victoria |
| 11 Royal North Shore Hospital | Clarke, Stephen |
| 12 Tamworth Hospital | George, Mathew |
| 13 Blacktown Hospital | Nagrial, Adnan |
| 14 Royal Hobart Hospital | Nott, Louise |
| 15 Royal Adelaide Hospital | Singhal, Nimit |
| 16 Moorabbin Hospital | Strickland, Andrew |
| 17 Gosford Hospital | Wong, Matthew |
| 18 Hospital Britanico | Bellaquero, Luciana |
| 19 天津市肿瘤医院 | 于振涛 |
| 20 浙江大学医学院附属第一医院 | 胡坚 |
| 21 中山大学肿瘤防治中心 | 傅剑华 |
| 22 复旦大学附属中山医院 | 谭黎杰 |
| 23 浙江省台州医院 | 陈保富 |
| 24 福建省肿瘤医院 | 柳硕岩 |
| 25 浙江省肿瘤医院 | 毛伟敏 |
| 26 复旦大学附属肿瘤医院 | 相加庆 |
| 27 北京肿瘤医院 | 陈克能 |
| 28 Chu Liege, Domaine Univ Du Sart Tilman | Collignon, Joelle |
| 29 Uz Gent | Geboes, Karen |
| 30 Clinique Sainte Elisabeth | Goeminne, Jean-Charles |
| 31 Universitair Ziekenhuis Antwerpen | Peeters, Marc |
| 32 Universitaire Ziekenhuizen Leuven Gasthuisberg | Van Cutsem, Eric |
| 33 Cliniques Universitaires Saint-Luc | Van Den Eynde, Marc |
| 34 Fundacao Pio Xii Hosp Cancer De Barretos | Abdalla, Kathia Cristina |
| 35 Liga Paranaense De Combate Ao Cancer Erasto Gaertner | Almeida, Thais |
| 36 Instituto do cancer do Estado de Sao Paulo ICESP | Bariani Giovanni |
| 37 Centro de Pesquisas Oncologicas de Santa Catarina-CEPON | Branco Ricardo |
| 38 Hospital Sirio Libanes | Fernandes Gustavo |
| 39 Associacao Hospital De Caridade De Ijui | Franke, Fabio Andre |
| 40 Hospital Sao Lucas Da Pucrs | Gelatti, Ana Caroline |
| 41 Hospital De Base - Famerp | Girotto, Gustavo |
| 42 Hospital Sirio Libanes | Hoff, Paulo |
| 43 Moraes, Eduardo | Nucleo De Oncologia Da Bahia |
| 44 PERSONAL Oncologia de Precisao e Personalizada | Murad, Andre Marcio |
| 45 COI Clinicas Oncologicas Integradas SA | Vieira, Fernando |
| 46 Montreal General Hospital | Alcindor, Thierry |
| 47 Centre integre universitaire de sante et de services sociaux de la Mauricie-et-d | Aucoin, Jean-Sebastien |
| 48 Hotel Dieu De Quebec | Couture, Felix |
| 49 Princess Margaret Cancer Centre | Elimova, Elena |
| 50 Ottawa Hospital Regional Cancer Centre | Jonker, Derek |
| 51 British Columbia Cancer Agency-Vancouver Ctr | Lim, Howard |
| 52 Cross Cancer Institute | Price Hiller, Julie |
| 53 Nova Scotia Health Authority QEII Health Sciences Centre | Snow, Stephanie |
| 54 London Regional Cancer Program | Vincent, Mark |
| 55 Klinika onkologie a radioterapie | Kubala, Eugen |
| 56 Onkologicka klinika | Melichar, Bohuslav |
| 57 Klinika komplexni onkologicke pece | Nemecek, Radim |
| 58 Aarhus University Hospital | Nordsmark, Marianne |
| 59 Hopital Saint Antoine | Andre, Thierry |
| 60 Centre Georges-Francois Leclerc | Ghiringhelli, Francois |
| 61 Centre Hospitalier Lyon Sud | Glehen, Olivier |
| 62 Hopital De Rangueil C H U De Toulouse | Guimbaud, Rosine |
| 63 Chu Pontchaillou | Lievre, Astrid |
| 64 Hopital Charles Nicolle C H U Rouen | Michel, Pierre |
| 65 INSTITUT SAINTE CATHERINE | Mineur, Laurent |
| 66 Hopital Claude Huriez | Piessen, Guillaume |
| 67 Hopital Saint Andre | Smith, Denis |
| 68 Universitaetsklinikum Tuebingen | Bitzer, Michael |
| 69 Klinikum Rechts Der Isar | Lorenzen, Sylvie |
| 70 Johannes -Gutenberg Universitat | Moehler, Markus |
| 71 Universitaets-Klinikum Marburg | Riera-Knorrenschild, Jorge |
| 72 Kliniken Essen-Mitte/Huyssens-Stift | Stahl, Michael |
| 73 Universitaets-Krankenhaus Eppendorf | Stein, Alexander |
| 74 Charite Campus Virchow Klinikum | Thuss-Patience, Peter |
| 75 University Hospital Of Cologne | Zander, Thomas |
| 76 Queen Mary Hospital | Lam, Ka On |
| 77 DE KK Onkologiai Intezet | Arkosy, Peter |
| 78 Onkologiai Osztaly | Bodoky, Gyorgy |
| 79 Orszagos Onkologiai Intezet | Hitre, Erika |
| 80 Onkologiai Centrum | Ruzsa, Agnes |
| 81 University College Hosp Galway | Leonard, Gregory |
| 82 Beaumont Hospital | Morris, Patrick |
| 83 Cork University Hospital | Power, Derek |
| 84 Rabin Medical Center, Institute of Oncology | Ben-Aharon, Irit Lando |
| 85 Rambam Medical Center | Beny, Alex |
| 86 Tel Aviv Sourasky Medical Center | Geva, Ravit |
| 87 Hadassah Ein-Kerem Hospital | Hubert, Ayala |
| 88 Sheba Medical Center | Shacham Shmueli, Einat |
| 89 Fondazione Policlinico Universitario A. Gemelli | Barone, Carlo |
| 90 Arcispedale S. Maria Nuova - A.O. Reggio Emilia | Carmine, Pinto |
| 91 IRCCS Istituto Nazionale Tumori | Di Bartolomeo, Maria |
| 92 Policlinico San Donato | Luporini, Alberto |
| 93 ASST Papa Giovanni XXIII | Merelli, Barbara |
| 94 Kumamoto University Hospital | Baba, Hideo |
| 95 The Cancer Institute Hospital Of Jfcr | Chin, Keisho The Cancer Institute Hospital Of Jfcr |
| 96 Osaka University Hospital | Doki, Yuichiro |
| 97 Keio University Hospital | Hamamoto, Yasuo |
| 98 Saitama Cancer Center | Hara, Hiroki |
| 99 Keiyukai Sapporo Hospital | Hosokawa, Masao |
| 100 National Cancer Center Hospital. | Kato, Ken |
| 101 Kindai University Hospital | Kawakami, Hisato |
| 102 Hokkaido University Hospital | Komatsu, Yoshito |
| 103 Chiba University Hospital | Matsubara, Hisahiro |
| 104 NHO Kyushu Cancer Center | Morita, Masaru |
| 105 Akita University Hospital | Motoyama, Satoru |
| 106 Kindai University Hospital | Kawakami, Hisato |
| 107 Hokkaido University Hospital | Komatsu, Yoshito |
| 108 Chiba University Hospital | Matsubara, Hisahiro |
| 109 NHO Kyushu Cancer Center | Morita, Masaru |
| 110 Akita University Hospital | Motoyama, Satoru |
| 111 Kagoshima University Hospital | Natsugoe, Shoji |
| 112 Hiroshima University Hospital | Okada, Morihito |
| 113 Kyushu University Hospital | Saeki, Hiroshi |
| 114 Tokyo Medical University Hospital | Tachibana, Shingo |
| 115 Tohoku University Hospital | Takahashi, Masanobu |
| 116 Toranomon Hospital | Takano, Toshimi |
| 117 Kagawa University Hospital | Tsuji, Akihito |
| 118 Gifu University Hospital | Yoshida, Kazuhiro |
| 119 Yonsei University Severance Hospital | Kim, Hye Ryun |
| 120 Asan Medical Center | Kim, Sung-Bae |
| 121 Instituto Nacional De Cancerologia | Calderillo Ruiz, German |
| 122 Fundacion Rodolfo Padilla Padilla A.C. | Gonzalez Trujillo, Jose Luis |
| 123 Supere Centro de Infusion S.A de C.V. | Guadarrama, Jorge |
| 124 Centro de Estudios y Prevencion Del Cancer, AC | Gutierrez Delgado, Francisco |
| 125 Instituto Nacional De Ciencias Medicas Y Nutricion S.Z. | Huitzil, Fidel |
| 126 Hospital Cardiologica De Aguascalientes | Urzua Flores, Claudia |
| 127 NKI AVL | Grootscholten, Cecile |
| 128 Universitair Medisch Centrum Groningen | Hospers, Geesiena |
| 129 MUMC | de Vos-Geelen, Judith |
| 130 Oncosalud Sac | Chong, Jorge |
| 131 Instituto Nacional De Enfermedades Neoplasicas | Montenegro, Paola |
| 132 Hospital Nacional Daniel Alcides Carrion | Revilla, Jose |
| 133 Hospital Nacional Cayetano Heredia | Tejada, Hermes |
| 134 Oddzial Kliniczny Chirurgii Klatki Piersiowej | Kuzdzal, Jaroslaw |
| 135 Oddzial Onkologii Klinicznej i Doswiadczalnej | Mackiewicz, Jacek |
| 136 Klinika Gastroenterologii Onkologicznej | Olesinski, Tomasz |
| 137 II Klinika Radioterapii i Chemioterapii | Suwinski, Rafal |
| 138 II Klinika Chirurgii Ogolnej, Gastroenterologicznej i Nowotworow Ukladu Pokarmow | Wallner, Grzegorz |
| 139 Fundacion De Investigacion | Acosta Rivera, Mirelis |
| 140 Fundeni Clinical Institute Gastroenterology; Hepatology Clin | Croitoru, Adina |
| 141 SC Oncopremium Team SRL | Filip, Dumitru |
| 142 Focus Lab Plus SRL | Iordan, Ingrid |
| 143 BENDIS CLINIC SRL | Mihailov, Anca |
| 144 SF. NECTARIE ONCOLOGY CENTER | Schenker, Michael |
| 145 S.C. Radiotherapy Center Cluj S.R.L. | Ungureanu, Andrei |
| 146 Saint-Petersburg Medical University Named After I.P.Pavlov | Dvoretskiy, Sergey |
| 147 N.N. Petrov National Medical Research Center of Oncology | Levchenko, Evgeny |
| 148 Republic Clinical Oncology Dispesary of MoH of Chuvashia | Subramanian, Somasundaram |
| 149 N.N. Blokhin National Medical Research Center of Oncology | Tryakin, Alexey |
| 150 National Cancer Center, Singapore | Ng, Chau Hsien Matthew |
| 151 National University Hospital | Sundar, Raghav |
| 152 Hospital Universitario Reina Sofia | Aranda, Enrique |
| 153 Hospital General Universitario Gregorio Maranon | Blanco, Montserrat |
| 154 Centro Integral Oncologico Clara Campal | Cubillo Gracian, Antonio |
| 155 H. Univ. Vall dHebron | Hierro, Cinta |
| 156 Universitaetsspital Basel | Hess, Viviane |
| 157 Kantonsspital St Gallen | Weisshaupt, Christian |
| 158 National Taiwan University Hospital | Hsu, Chih-Hung |
| 159 China Medical University Hospital | Lin, Chen-Yuan |
| 160 National Cheng Kung University Hospital | Yen, Chia-Jui |
| 161 Ataturk University | Basol Tekin, Salim |
| 162 Gazi Universitesi Tip Fakultesi | Benekli, Mustafa |
| 163 Istanbul Universitesi Cerrahpasa Tip Fakultesi Onkoloji | Ozguroglu, Mustafa |
| 164 Baskent University Adana Hospital | Sezer, Ahmet |
| 165 The University Of Texas MD Anderson Cancer Center | Ajani, Jaffer |
| 166 Pacific Hematology Oncology Associates | Baron, Ari |
| 167 Jersey Shore University Medical Center | Bauer, Thomas |
| 168 Sarah Cannon Research Institute | Bendell, Johanna |
| 169 University Of Chicago | Catenacci, Daniel |
| 170 Beth Israel Deaconess Medical Center | Cleary, James |
| 171 Dana Faber Cancer Institute | Cleary, James |
| 172 Mass General/North Shore Cancer Center for Outpatient Care | Cleary, James |
| 173 Massachusetts General Hospital | Cleary, James |
| 174 NYU Langone Medical Center | Cohen, Deirdre |
| 175 University Of Colorado | Davis, Sarah |
| 176 Fox Chase Cancer Center | Denlinger, Crystal |
| 177 University Hospitals of Cleveland | Eads, Jennifer |
| 178 Sacred Heart Medical Group | Eldawy, Tarek |
| 179 Vanderbilt University Med Ctr | Goff, Laura |
| 180 Hackensack University Medical Center | Gutierrez, Martin |
| 181 Allegheny Health Network | Jobe, Blair |
| 182 Johns Hopkins Sidney Kimmel Comprehensive Cancer Center | Kelly, Ronan |
| 183 Georgetown University Med Ctr | Kim, Sunnie |
| 184 Ucsf Cancer Center | Ko, Andrew |
| 185 Univ. Of Southern Calif. /Norris Comprehensive Cancer Center | Lenz, Heinz-Josef |
| 186 University Of Miami Sylvester Comprehensive Cancer Center | Lockhart, Albert |
| 187 University Of Wisconsin | Lubner, Sam |
| 188 Washington University School of Medicine | Park, Haeseong |
| 189 SCRI Florida Cancer Specialists North | Patel, Vijay |
| 190 Albert Einstein Cancer Center At The Montefiore Medical Park | Rajdev, Lakshmi |
| 191 Levine Cancer Institute | Salmon, Stuart |
| 192 Lehigh Valley Hospital | Shah, Usman |
| 193 University of Washington | Shankaran, Veena |
| 194 Cancer Specialists of North FL | Telivala, Bijoy |
| 195 Duke Cancer Center | Uronis, Hope |
| 196 Oregon Health & Sci Univ | Vaccaro, Gina |
| 197 Dallas VA Medical Center | Wang, David |
| 198 Scott & White Memorial Hospital And Clinic | Wong, Lucas |
| 199 Florida Cancer Specialists | Zafar, Syed |
| 200 University College Hospital | Bridgewater, John |
| 201 Royal Marsden Hospital | Chau, Ian |
| 202 Royal Marsden Nhs Foundation Trust | Chau, Ian |
| 203 Southampton General Hospital | Iveson, Tim |
| 204 The Christie NHS Foundation Trust | Mansoor, Wasat |
| 205 Guy'S And St Thomas'S Nhs Foundation Trust | Ngan, Sarah |